中国组织工程研究 ›› 2015, Vol. 19 ›› Issue (53): 8549-8553.doi: 10.3969/j.issn.2095-4344.2015.53.004

• 人工假体 artificial prosthesis • 上一篇    下一篇

基于生物学水平全髋关节置换修复强直性脊柱炎性髋关节病变:2年随访

丁良甲1,刘莹丽2,刘晓民1,马 钢1,刘长路1   

  1. 内蒙古医科大学第二附属医院,1关节外科,2康复科,内蒙古自治区呼和浩特市 010030
  • 收稿日期:2015-10-01 出版日期:2015-12-24
  • 通讯作者: 刘莹丽,内蒙古医科大学第二附属医院康复科,内蒙古自治区呼和浩特市 010030
  • 作者简介:丁良甲,男,1980年生,辽宁省沈阳市人,2011年内蒙古医科大学毕业,硕士,主治医师,主要从事髋关节病病理学研究。

Total hip arthroplasty repairs ankylosing spondylitis-associated hip joint lesion based on the biological level: 2-year follow-up

Ding Liang-jia1, Liu Ying-li2, Liu Xiao-min1, Ma Gang1, Liu Chang-lu1   

  1. 1Department of Joint Surgery, 2Department of Rehabilitation, the Second Affiliated Hospital of Inner Mongolia Medical University, Hohhot 010030, Inner Mongelia Autonomous Region, China
  • Received:2015-10-01 Online:2015-12-24
  • Contact: Liu Ying-li, Department of Rehabilitation, the Second Affiliated Hospital of Inner Mongolia Medical University, Hohhot 010030, Inner Mongelia Autonomous Region, China
  • About author:Ding Liang-jia, Master, Attending physician, Department of Joint Surgery, the Second Affiliated Hospital of Inner Mongolia Medical University, Hohhot 010030, Inner Mongelia Autonomous Region, China

摘要:

背景:由于医疗技术、假体材料学的不断发展,针对强直性脊柱炎髋关节受累病变的患者常采用人工全髋关节置换进行治疗。且此类疾病中青年患者居多,因此最大限度恢复髋关节功能,恢复脊柱、骨盆、髋关节生物力学平衡,延长髋关节使用寿命,对患者生活具有重要意义。
目的:基于生物学水平观察全髋关节置换对于强直性脊柱炎性髋关节病变的修复效果。
方法:选择2010年12月至2014年12月(含2年随访时间)内蒙古医科大学第二附属医院关节外科收治的60例强直性脊柱炎髋关节病变患者,均采用生物型全髋关节假体行全髋关节置换治疗。随访2年,对置换前、末次随访患者的髋关节活动度(总活动度、屈伸、内收、外展、内旋、外旋)、髋关节Harris评分、疼痛目测类比评分、生活质量等进行观察、统计及对比分析。
结果与结论:末次随访患者髋关节活动度各指标均较治疗前明显恢复,差异有显著性意义(P < 0.05)。治疗前患者髋关节疼痛较重,功能差,生活质量差;末次随访患者恢复较好,疼痛明显缓解,髋关节功能有效恢复,生活质量显著提高,差异均有显著性意义(P < 0.05)。提示采用生物型全髋关节假体对强直性脊柱炎性髋关节病变患者进行全髋关节置换可有效恢复髋关节的生理解剖结构,恢复髋关节的关节功能及活动度,缓解疼痛,提高生活质量。 

关键词: 骨科植入物, 人工假体, 强直性脊柱炎性髋关节病变, 生物型全髋关节置换, 回顾性分析, 随访研究

Abstract:

BACKGROUND: Due to the continuous development of medical technology and prosthetic material study, patients with ankylosing spondylitis-associated hip joint lesion are often treated with artificial total hip arthroplasty. Because the majority patients of this kind of disease are young patients, it is of great importance for the patients’ life quality through maximizing the recovery of hip function, restoring the biomechanical balance of spine, pelvis and hip joint and prolonging the life of hip joint.
OBJECTIVE: To observe the repair effect of total hip arthroplasty in treatment of ankylosing spondylitis-associated hip joint lesion based on the biological level.
METHODS: Totally 60 patients with ankylosing spondylitis-associated hip joint lesion who received the treatment

 

at Department of Joint Surgery, the Second Affiliated Hospital of Inner Mongolia Medical University from December 2010 to December 2014 (including 2 years of follow-up) were selected and conducted total hip arthroplasty using biological type total hip prosthesis. During 2 years of follow-up, hip activity (total activity, flexion and extension, adduction, abduction, internal rotation, external rotation), hip Harris score, pain visual analog scale score, quality of life of patients were observed, counted and comparatively analyzed before replacement and in the final follow-up. 
RESULTS AND CONCLUSION: The hip joint activity and other various indexes of patients in the final follow-up significantly recovered compared with before treatment (P < 0.05). Before treatment, the hip joint pain of patients was severe, the function and the quality of life were poor, however, in the final follow-up, the pain of patients was obviously relieved, hip function effectively recovered and quality of life improved significantly, the differences were statistically significant (P < 0.05). These results suggest that the application of total hip arthroplasty by using biological type total hip prosthesis on patients with ankytosing spondylitis-associated hip joint lesion can effectively restore physiological and anatomical structure of the hip joint, restore the function and activity of hip joint, relieve pain, and improve the quality of life.  

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