中国组织工程研究 ›› 2012, Vol. 16 ›› Issue (5): 779-782.doi: 10.3969/j.issn.1673-8225.2012.05.005

• 肾移植 kidney transplantation • 上一篇    下一篇

自体纯化冷冻微粒脂肪注射移植修复面部皮肤软组织老化性萎缩凹陷★

谢红炬,邓  颖,李  明,罗惠中,陈  碾   

  1. 南华大学附属第一医院医疗美容科,湖南省衡阳市   421001
  • 收稿日期:2011-07-26 修回日期:2011-09-14 出版日期:2012-01-29
  • 作者简介:谢红炬★,男,1968年生,湖南省衡阳市人,汉族,2006年南华大学毕业,硕士,教授,主任医师,硕士生导师,主要从事脂肪移植、脂肪干细胞研究。xhj1251@sina.com

Autologous purified freezing fat microparticle injection for facial rejuvenation

Xie Hong-ju, Deng Ying, Li Ming, Luo Hui-zhong, Chen Nian   

  1. Department of Plastic and Reconstructive Surgery, First Affiliated Hospital of South China University, Hengyang  421001, Hunan Province, China
  • Received:2011-07-26 Revised:2011-09-14 Online:2012-01-29
  • About author:Xie Hong-ju★, Master, Professor, Chief physician, Master’s supervisor, Department of Plastic and Reconstructive Surgery, First Affiliated Hospital of South China University, Hengyang 421001, Hunan Province, Chinaxhj1251@sina.com

摘要:

背景:以少量、反复、多次脂肪注射,是目前提高脂肪移植成活率的理想方法。
目的:总结自体纯化冷冻微粒脂肪注射移植在面部年轻化的应用效果。
方法:对64例面部皮肤软组织老化萎缩凹陷患者,在其腹部或大腿用肿胀吸脂术抽吸微粒脂肪,经过低速低压离心纯化微粒脂肪,并在-20 ℃下低温冷冻,37 ℃下复温培养1 h后,检测脂肪组织活力,注射移植填充面部老化凹陷区域。
结果与结论:64例(186个部位)中21例接受1次微粒脂肪注射移植,35例接受2次微粒脂肪注射移植,8例接受3次微粒脂肪注射移植。患者脂肪移植后均随访6个月以上,面部老化症状明显改善,效果满意、持久,吸收率低,无感染、脂肪液化等并发症发生。提示自体纯化冷冻脂肪微粒注射移植效果明显、吸收率低、可重复注射、易于患者接受。

关键词: 自体脂肪微粒, 纯化, 冷冻, 移植, 面部年轻化

Abstract:

BACKGROUND: Presently, slight and repeated injection is a good method to elevate the survival rate of implanted fat tissue.
OBJECTIVE: To explore the clinical application of autologous purified freezing microparticle fat injection in facial rejuvenation.
METHODS: Totally 64 facial aging patients presenting with atrophy and depression of facial soft tissue were treated with injecting transplantation of microparticle fat which was obtained from patient’s abdomen or thighs by using tumescent liposuction technique. Microparticle fat was purified by low-speed and low-pressure centrifugal, then undergoing -20 ℃ hypothermic freezing and 37 ℃ rewarming for 1 hour. Vitality of fat tissues was detected.
RESULTS AND CONCLUSION: Totally 21 cases of 64 cases (186 positions) received one time injecting transplantation, 35 cases received two times injecting transplantation, and eight cases received three times injecting transplantation. All the patients were followed for 6 months, the effects were satisfactory and there was no complication. Autologous purified freezing microparticle fat injecting transplantation is characterized as low absorptivity, duplicate injection, and acceptable easily.

中图分类号: