Department of Neurology, First Affiliated Hospital, Chongqing Medical University, Chongqing   400016, China

Qin Yang☆, Doctor, Associate professor, Department of Neurology, First Affiliated Hospital, Chongqing Medical University, Chongqing   400016, China Supported by: the Science Foundation of Education Committee of Chongqing City, No. KJ070310* Yang Q, Xie P. Sonic hedgehog signaling during nervous system development. Neural Regen Res 2008;3(7):782-5

Abstract

The Hedgehog signaling pathway plays a key role in embryonic development and organ formation. Sonic hedgehog signaling participates in nervous system development, regulates proliferation and differentiation of neural stem cells, controls growth and targeting of axons, and contributes to specialization of oligodendrocytes. For further studies of the Sonic hedgehog signaling pathway and for the development of new drugs in the treatment of nervous system diseases, it is beneficial to understand these mechanisms.

Key Words: development; nervous system; review; Sonic hedgehog

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