2011.12
Publisher：yinlzxb Publish Time：Saturday, May 28, 2011
Source：NRR |
| Research and Reports |
| Traditional Chinese Medicine and Neuroregeneration |
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The Chinese herbal formula Tongluo Jiunao promotes expression of brain-derived neurotrophic factor/tropomyosin-related kinase B pathways in a rat model of ischemic brain injury☆
Neural Regeneration Research 2011;6(12):885-891
Peiman Alesheikh1, Huiling Tang1, Pengtao Li2, Wei Zhang3, Yanshu Pan1, Arezou Mashoufi1, Liyun Zhao3, Runjun Wang1, Bo Di1, Yangyang Yan1 |
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The present study utilized Xue Sai Tong as a positive control to study mechanisms of neuroprotection, and analyzed brain-derived neurotrophic factor and tropomyosin-related kinase B expression following Tongluo Jiunao injection. | | |
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Effects of GBE50 on hippocampal CA1 synaptic plasticity, learning and memory in an experimental rat model of aging***★
Neural Regeneration Research 2011;6(12):892-897
Lili Wu, Xianwen Dong, Gaiying He, Zhixiong Zhang, Ying Xu, Xingyu Wang, Yun Li
Supported by: the Scientific Research Program of the Shanghai Science and Technology Commission, No. 09ZR1432100*; the Key Subject Construction Program of Shanghai Education Commission, No. J50301*; the Scientific Research Innovation Program of Shanghai Education Commission, No. 08YZ59* |
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GBE50 is a standard extract of the ginkgo leaf, which was developed by a Chinese company. This study utilized GBE50 to treat an experimental rat model of aging and compared with EGB761. Results demonstrate that GBE50 and EGB761 enhanced hippocampal synaptic plasticity and improved the learning and memory of aging rats. | | |
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Effects of compound rehmannia formula on dopamine transporter content in the corpus striatum of Parkinson’s disease rats treated with levodopa***★
Neural Regeneration Research 2011;6(12):898-902
Ruijng Luo, Jiancheng He
Supported by:the National Natural Science Foundation of China, No. 30672684*, 30973722*; the Third Intention Key Disciplinary Areas of Shanghai, No. S30302* |
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Using qualitative and quantitative analyses, this study objectively explored changes in the amount of dopamine transporter in the corpus striatum in the lesioned side of the bran in rats treated with L-3,4-dihydroxyphenylalanine, to evaluate the potential curative effects of compound rehmannia formula in reducing side-effects of levodopa drugs. | | |
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Midbrain enkephalin expression in a rat migraine model following intragastric scorpion powder administration☆
Neural Regeneration Research 2011;6(12):903-907
Gang Yao1, 2, Xiangdan Luo3, Dihui Ma1, Tingmin Yu2 |
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The present study was the first to demonstrate that scorpion powder exerted analgesic effects on migraine by upregulating proenkephalin mRNA expression and increasing methionine-enkephalin content in a rat migraine model. | | |
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Brazilein intervention for sciatic nerve injury in BALB/c mice**☆
Neural Regeneration Research 2011;6(12):908-913
Zhan Zhang, Jian Cao, Weitian Yin, Lisen Li, Yuxi Jia, Haoyu Liu, Mingming Zhao, Rihua Jiang
Supported by:Doctoral Fund of Jilin University, No. 20030183014*; a grant from Administration of Traditional Chinese Medicine of Jilin Province, No. 20080934* |
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The current study indicated that brazilein can increase S100 protein expression in injured segments of the spinal cord, and promote sciatic nerve repair after sciatic nerve injury in BALB/c mice. Both high (16 g/kg) and medium (8 g/kg) doses were found to exert significant effects. | | |
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