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2011.15

Publisher:mengjjzbs  Publish Time:Friday, June 24, 2011 
Source:NRR

    Research and Reports
     Meta-analysis
1  Meta-analysis of Ginkgo biloba extract for the treatment of Alzheimer’s disease★ Neural Regeneration Research 2011;6(15): 1125-1129
Zheng Yang1, Wenjie Li2, Tao Huang3, Jianmin Chen1, Xiao Zhang1
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  Research Highlights
This study used high-quality case-control literature to address the use of Ginkgo biloba extract for the treatment of Alzheimer’s disease. Meta-analysis revealed that Ginkgo biloba extract exhibits good therapeutic effects on mild and moderate Alzheimer’s disease.
    Traditional Chinese Medicine and Neuroregeneration
2  Gentianine protects hippocampal neurons in a rat model of recurrent febrile convulsion*★
Neural Regeneration Research 2011;6(15): 1130-1135
Xuewei Liu1, Shumin Liu1, Na Wang2, Fang Lu2, Min Cao2
Supported by: the Key Project of Technology of Ministry of Education, No. 2007029*
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Gentianine was found to relieve neuronal injury in hippocampal CA1 caused by febrile convulsions by increasing glutamate acid decarboxylase activity, decreasing glutamate levels and increasing γ-aminobutyric acid levels.
3  Protective effects of combined Astragalus membranaceus and magnesium ions on global brain ischemia**☆
Neural Regeneration Research 2011;6(15): 1136-1140
Yifeng Miao1, Bing Li1, Yuchang Lin1, Xiaojie Lu1, Bin Wu2, Yongming Qiu2
Supported by: the National Natural Science Foundation of China, No. 81000498*; and the Natural Science Foundation of Nanjing Medical University, No. 09MJMUM107*
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Compared with treatment with Astragalus membranaceus or magnesium alone, combined treatment with both Astragalus membranaceus and magnesium significantly decreased the number of apoptotic cells and cleaved caspase-3 protein expression in the hippocampus, and substantially improved learning and memory function in rats with global brain ischemia.
4  Anti-oxidant effect of picroside II in a rat model of cerebral ischemia/reperfusion injury**★
Neural Regeneration Research 2011;6(15): 1141-1146
Li Sun1, Xiaodan Li2, Ling Wang1, Lihua Qin3, Yunliang Guo2, Zhen Zhou2
Supported by: the National Natural Science Foundation of China, No. 30873391*, 81041092*
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Picroside II injection via the tail vein exerts a neuroprotective effect, possibly by downregulating inducible nitric oxide synthase expression, increasing SOD activity, and inhibiting neuronal apoptosis.
5  Extract from Buthus martensii Karsch is associated with potassium channels on glioma cells*☆
Neural Regeneration Research 2011;6(15): 1147-1150
Mingxian Li1, Hongmei Meng2, Shao Wang3, Min Huang3, Li Cui2, Weihong Lin2
Supported by: the Science and Technology Development Program of Jilin Province, No. 20050407-6*
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  Research Highlights
Antigliomatin, an extract from scorpion venom of Buthus martensii Karsch in China, can inhibit glioma growth via potassium channels on the surface of glioma cells.


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