2011.16
Publisher：yinlzxb Publish Time：Monday, July 25, 2011
Source：NRR |
| Research and Reports |
| Stem Cells and Neuroregeneration |
1  |
Ameliorative effects of human adipose tissue-derived mesenchymal stem cells on myelin basic protein-induced experimental autoimmune encephalomyelitis in Lewis rats●
Neural Regeneration Research 2011;6(16): 1205-1210
Myung-Soon Ko1, 2, Hyeong-geun Park2, Young-Min Yun1, Jeong Chan Ra2, Taekyun Shin1, Kyoung-Kap Lee1 |
| |
|Abstract|HTML| PDF|Supplementary    |Editor’s Choice
|Article Category|Instruction for Authors|Sample Article|Submission |
 |
 Research Highlights |
 |
The present results suggest that human adipose tissue-derived mesenchymal stem cells significantly ameliorate the clinical severity of acute inflammatory central nervous system diseases in a dose- and time-dependent manner. Our findings indicate that these effects operate, at least in part, through the ample production of anti-inflammatory cytokines, such as interleukin-10 and indoleamine 2, 3-dioxygenase, and by inducing a shift toward the Th2 phenotype in the lymph node. | | |
| 2 |
Adenovirus-mediated human brain-derived neurotrophic factor gene-modified bone marrow mesenchymal stem cell transplantation for spinal cord injury*☆
Neural Regeneration Research 2011;6(16): 1211-1216
Changsheng Wang, Jianhua Lin, Chaoyang Wu, Rongsheng Chen
Supported by: Research Fund for the Doctoral Program of Higher Education of China, No. 20060392003* |
| |
|Abstract|HTML|PDF|Supplementary |Editor’s Choice
|Article Category|Instruction for Authors|Sample Article|Submission |
|
| Research Highlights |
 |
Rat bone marrow mesenchymal stem cells expressing brain-derived neurotrophic factor were obtained by gene transfection, and transplanted into rats with spinal cord injury. These cells could thus play a dual role, simultaneously providing stem cells and neurotrophic factors. | | |
| 3 |
Nogo-A expression in injured spinal cord following human olfactory mucosa-derived olfactory ensheathing cells transplantation*☆
Neural Regeneration Research 2011;6(16): 1217-1221
Bin Wang1, Qiang Li2, Xijing He3, Weixiong Wang1
Supported by: the Doctoral Priming Foundation of Guangzhou Medical University* |
| |
|Abstract|HTML|PDF|Supplementary |Editor’s Choice
|Article Category|Instruction for Authors|Sample Article|Submission |
|
| Research Highlights |
 |
Human olfactory mucosa-derived olfactory ensheathing cell transplantation into rats with acute spinal cord injury promotes regeneration, which is possibly associated with reduction of Nogo-A expression. | | |
|
|
| 5 |
Effects of caveolin-1 on bone marrow mesenchymal stem cells differentiating into neuron-like cells-An atomic force microscopy observation**★
Neural Regeneration Research 2011;6(16): 1227-1231
Jingjing Lu, Lijun Jing, Yonglin Jia, Jinyi Li, Liudong Wang, Tao Peng, Yanjie Jia
Supported by: the National Natural Science Foundation of China, No. 30770758*; the Natural Science Research Program of Henan Provincial Department of Education, No. 2008A320032* |
| |
|Abstract|HTML|PDF|Supplementary |Editor’s Choice
|Article Category|Instruction for Authors|Sample Article|Submission |
|
| Research Highlights |
 |
This study used atomic force microscopy to observe morphological changes in rat bone marrow mesenchymal stem cells transfected with caveolin-1. The lipid raft marker protein caveolin-1 was found to regulate mesenchymal stem cell differentiation into neuron-like cells. | | |
|