2011.14
Publisher：mengjjzbs Publish Time：Wednesday, June 15, 2011
Source：NRR |
| Research and Reports |
| Neurodegenerative Diseases and Neuroregeneration |
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Beta-amyloid precursor protein cleavage enzyme-1 expression in adult rat retinal neurons in the early period after lead exposure**☆
Neural Regeneration Research
2011;6(14): 1045-1051
Jufang Huang1, Kai Huang1, 2, Lei Shang1, Hui Wang1, Xiaoxin Yan1, Kun Xiong1
Supported by: the National Natural Science Foundation of China, No. 30900773*; the National University Basic Research Foundation of China, No. 2010QZZD022* |
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The current study examined protein expression in the retina to elucidate the mechanisms underlying Alzheimer’s disease. The results suggested that β-amyloid precursor protein cleavage enzyme-1 may be a major factor in inducing excessive β-amyloid production in the early period after lead exposure | | |
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Real-time surface electromyography in Parkinson’s disease patients during exercise-induced muscle fatigue☆
Neural Regeneration Research
2011;6(14): 1057-1061
Lei Gao1, 2, Tong Zhang1, 2, Xia Gao3 |
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This study examined surface electromyography in patients with Parkinson’s disease. The results revealed that patients showed a stronger increase in mean square amplitude, but a weaker decrease in median frequency and mean power frequency, compared with healthy controls. The specificity of surface electromyography may be related to the mechanisms underlying fatigability in Parkinson’s disease patients | | |
| Techniques and Methods |
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Expression of mRNA-encoding subunits of N-methyl-D-aspartate receptor in the hypothalamus in sustained monaural block of auditory air-conduction model rats☆
Neural Regeneration Research
2011;6(14): 1062-1066
Ping Wan1, Xiaojian Lai2, Cheng Huang3, Xinde Sun4 |
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The results indicated that the mRNA expression levels of hypothalamic N-methyl-D-aspartate receptor subunits NR1, NR2A, NR2B and NR2C are influenced by the auditory environment | | |
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Inhibition of central sympathetic nervous tone improves cardiomyocyte contraction by increasing the response of beta 2-adrenergic receptor in aged rats**☆
Neural Regeneration Research
2011;6(14): 1067-1071
Ying Wang1, Zhi Zhao2, Qin Wu2, Yanling Hao2, Chuanying Xu2, Yiwei Sun2, Hong Sun2, Changdong Yan2, Dongye Li3
Supported by: the President Support Funding of Xuzhou Medical College, No. 09KJZ31*; the Social Development Program of Xuzhou, No. XM08C063* |
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The present study verified that reduced central sympathetic tones improved cardiomyocyte contraction in aged rats by improving responses of β2-adrenergic receptor to isoprenaline | | | 插入分页符
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Specific responses of monoamine neurotransmitters to various acute stressors*☆○
Neural Regeneration Research
2011;6(14): 1072-1076
Rongrong He1, Guanyu Lin1, Yifang Li1, Keiich Abe2, Xinsheng Yao1, Hiroshi Kurihara1
Supported by: the Fundamental Research Funds for the Central Universities, No. 21611203* |
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This study compared the effects of different acute stressors, such as blood-drawing stimulation or restraint, on monoamine neurotransmitter levels in plasma, the cortex and midbrain of mice. We confirmed that histaminergic, serotonergic or dopaminergic systems act and respond specifically on different regions of the brain, and in plasma, depending on the type of stressor | | |
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Effects of lead exposure on histological structure and antioxidant capacity in the cerebellum of 30-day-old mice★
Neural Regeneration Research
2011;6(14): 1077-1081
Yu Wang, Shengqing Wang
Supported by: the Fundamental Research Funds for the Central Universities, No. 21611203* |
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This study examined the effects of lead on histological structure and antioxidant capacity 30-day-old mice. The activities of superoxide dismutase, catalase, alkaline phosphatase, acid phosphatase and malondialdehyde content were examined. The results demonstrated that lead exposure exerted strong effects on histological structure and inhibited antioxidant capacity in the cerebellum in 30-day-old mice | | |
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Effect of propofol pretreatment on apoptosis in rat brain cortex after focal cerebral ischemia and reperfusion☆
Neural Regeneration Research
2011;6(14): 1086-1090
Haiyan Xu1, Chengwei Zhang2, Chunxiao Zhang1 |
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Propofol pretreatment significantly upregulated Bcl-2 expression, and downregulated Bax expression and caspase-3 activity. Propofol inhibited cell apoptosis in focal cerebral ischemia-reperfusion injury. This neuroprotective effect is most likely achieved via the mitochondrial pathway | | |
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Effects of isoflurane and sevoflurane postconditioning and changes in JNK1/2 pathway activity on rat brain slices subjected to oxygen and glucose deprivation in vitro*★
Neural Regeneration Research
2011;6(14): 1091-1096
Sheng Wang1, Zhigang Dai1, Xiwei Dong1, Suxiang Guo1, Yang Liu1, Shan Jiang2, Zhiping Wang3
Supported by: the Natural Science Foundation of Shihezi University, No. RCZX200688* |
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Isoflurane and sevoflurane post-conditioning exerted neuroprotective effects in hippocampal slices after oxygen and glucose deprivation injury in vitro by inhibiting JNK1/2 expression | | |
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Magnetic resonance imaging with three-dimensional fast imaging employing steady-state acquisition with phase-cycled and short T1 inversion recovery pulse sequence for evaluating brachial plexus injury★
Neural Regeneration Research
2011;6(14): 1097-1102
Dianxiu Ning1, Meiyu Sun1, Bo Sun1, Li Zhao1, Weisheng Zhang1, Lijun Wang1, Shaowu Wang1, Ailian Liu1, Jianlin Wu1, Zhijin Lang1, Di Ning2, Guanfu Liu3, Xiaochen Ji3, Xiufeng Wang1 |
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Magnetic resonance imaging combined with 3D-fast imaging employing steady-state acquisition with phase-cycled and short T1 inversion recovery pulse sequence may be useful for visualizing the site, severity and scope of brachial plexus injury through continuous scanning | | |
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Identification of the primary motor area by three-dimensional reconstruction of the corticospinal tract using diffusion tensor imaging**★
Neural Regeneration Research
2011;6(14): 1103-1107
Guojun Deng1, Luo Li1, Guimei Chen2, Erming Zeng1, Xiangzuo Xiao2, Meihua Li1, Tao Hong1, Donghai Li1
Supported by: the Science and Research Project of Jiangxi Provincial Department of Science and Technology, No. 07-1012*; a grant from the Jiangxi Provincial Department of Education, No. GJJ08116 |
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(1) Two regions of interest were established for corticospinal tract fiber tracking, one at the pons level and the other at the cerebral peduncle level, which decreased the influence of “crossing” or “kissing” fibers and increased reliability of fiber tracking results.
(2) As a classic anatomical landmark, the brain stem is easily recognized and avoids difficulties of establishing regions of interest in the internal capsule, which could be displaced by lesion | | |
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