2011.24 - CRTER NRR BRM JCS SCIR TCT TCMC TOGT

2011.24

Publisher：yinlzxb Publish Time：Tuesday, October 11, 2011
Source：NRR

Research and Reports

Traditional Chinese Medicine and Neuroregeneration

Effects of curcumin on hippocampal Bax and Bcl-2 expression and cognitive function of a rat model of Alzheimer’s disease★
Neural Regeneration Research 2011;6(1845-1849):
Yunliang Wang1, Honglei Yin1, Jiyu Lou2, Bing Han1, Xinyue Qin3, Fanchao Meng2, Shuang Geng1, Yajun Liu1
Supported by:the National Natural Science Foundation of China, No. 30770762*

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Research Highlights

BACKGROUND:Curcumin can regulate Bax and Bcl-2 expression, thereby improving spatial learning and memory in rats with Aβ1-40-induced Alzheimer’s disease.

Curcumin protects against interleukin-6-induced rapid Ca2+ influx in rat hippocampal neurons★
Neural Regeneration Research 2011;6(1850-1854):
Qinying Deng1, 2, 3, Tao Huang1, 2, 3, Hongmei Tang1, 2, 3, Xingming Zhong4, Sujian Xia5, Xiangcai Wei4, Jun Dong1, 2, 3
Supported by:the Natural Science Foundation of Guangdong Province, No. 06105246*, 9151040701000*; Science and Technology Foundation of Guangzhou, No. 2010Y1-C291*; Science and Technology Foundation of Guangdong Province, No. 2010B030700016*, 2008A030201003*; Leading Academic

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Research Highlights

BACKGROUND:Curcumin was found to exert neuroprotective effects on rat hippocampal neurons by inhibiting the rapid influx of Ca2+ induced by interleukin-6 and maintaining calcium homeostasis.

Effects of butternut squash extract on dentate gyrus cell proliferation and spatial learning in male adult rats★
Neural Regeneration Research 2011;6(1855-1859):
Mohsen Marzban1, Sara Soleimani Asl2, Hassan Fallah Huseini3, Mahdi Tondar4, Samira Choopani5, Mehdi Mehdizadeh6, 7
Supported by:a grant from the Research Institute for Islamic and Complementary Medicine (RICM), Tehran University of Medical Sciences, No. p26/m/t/1088*

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Research Highlights

BACKGROUND:
Butternut squash extract decreased escape latency and distance traveled in the Morris water maze in male rats
Butternut squash extract increased the time spent in target quadrant in the Morris water maze in male rats
Butternut squash extract caused proliferation of dentate gyrus cells in male rats

Tolerance of nestin+ cholinergic neurons in the basal forebrain against colchicine-induced cytotoxicity★
Neural Regeneration Research 2011;6(1860-1864):
Jing Yu1, Kaihua Guo1, Dongpei Li1, Jinhai Duan2, Juntao Zou1, Junhua Yang1, Zhibin Yao1
Supported by:the National Natural Science Foundation of China, No. 30700436*

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Research Highlights

BACKGROUND:After 28 days of colchicine treatment, the number of nestin+ cholinergic neurons increased but the number of nestin- cholinergic neurons, parvalbumin-positive neurons decreased. These results show that nestin+ cholinergic neurons have better tolerance to colchicine-induced neurotoxicity.

Inhibitory effects of Shuanghuanglian injection on nuclear factor-kappa B expression in mice with viral encephalitis in a time- and dose-dependent manner★
Neural Regeneration Research 2011;6(1865-1869):
Ye Tian, Caiping Han, Naibing Gu, Zhengli Di, Gejuan Zhang, Hui Lei
Supported by:the Health Research Fund from Health Department of Shaanxi Province, China, No. 04015*

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Research Highlights

BACKGROUND:The results of this study suggested that Shuanghuanglian injection can reduce nuclear factor-kappa B expression in mice with viral encephalitis in a time- and dose-dependent manner.

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