2011.30
Publisher：yinlzxb Publish Time：Monday, November 21, 2011
Source：NRR |
| Research and Reports |
| Traditional Chinese Medicine and Neuroregeneration |
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Fructus Broussonetae extract improves cognitive function and endoplasmic reticulum stress in Alzheimer’s disease models★
Neural Regeneration Research 2011;6(2325-2331):
Yinghong Li1, Li Hu1, Zhengzhi Wu1, 2, Zhiling Yu3, Meiqun Cao2, Kehuan Sun1, Yu Jin1, Anmin Wu1, Andrew CJ Huang4
Supported by: the National Natural Science Foundation of China, No. 30973779* |
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BACKGROUND:
(1) This study is the first to elucidate the molecular pathological characteristics of endoplasmic reticulum stress in models of Alzheimer's disease induced by Aβ25-35 and D-galactose.
(2) We investigated the effects of Fructus Broussonetiae extract, a traditional Chinese medicinal herb, on cognitive function and endoplasmic reticulum stress in Alzheimer's disease pathological models. | | |
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Influence of flavone extract from cultivated saussurea on learning and memory in a mouse model of Alzheimer's disease
A comparison with estradiol benzoate★
Neural Regeneration Research 2011;6(2332-2336):
Weiqiang Chen1, 2, Shuiming Gong3, Yan Li4, Ming Li1, 2, Zemin Yang1, 2, Lirong Zhang1, 2
Supported by: the National Natural Science Foundation of China, No. 30901980*; the Foundation for Distinguished Young Talents in Higher Education of Guangdong, China, No. 51343003*; a grant from Traditional Chinese Medicine City of South China at Zhongshan, Guangdong Province, No. 2009H016*; the Medical Scientific Research Foundation Program of Guangdong Province, No. A20100285* |
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BACKGROUND:Flavone extract from artificially cultivated saussurea can improve learning and memory deficits in a mouse model of Alzheimer's disease. | | |
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Kongsheng Zhenzhong pill’s effect on the learning and memory ability and its neuroprotective effects in vascular dementia rats★
Neural Regeneration Research 2011;6(2342-2346):
Xuming Ji1, Huayun Yu1, Bin Ouyang1, Guowei Liu1, Zhichun Wu1, Heng Liu2, Fang Du3
Supported by:the National Basic Research Program of China (973 Program), No. 2007CB512601*; Science and Technology Development Plan of TCM in Shandong Province, No. 2009-006*; Science and Technology Plan in Colleges and Universities of Shandong Province, No. J11LF60*, J11LF08* |
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|Abstract|HTML|PDF|Supplementary |Editor’s Choice
|Article Category|Instruction for Authors|Sample Article|Submission |
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| Research Highlights |
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BACKGROUND:The Kongsheng Zhenzhong pill significantly decreased the expression of N-methyl-D-aspartate receptor 1 mRNA and protein, the content of nitric oxide and the concentration of calcium in the brain tissues of vascular dementia rats. Kongsheng Zhenzhong pills up-regulated the expression of nerve growth factor and glial cell line-derived neurotrophic factor proteins in the hippocampus and cerebral cortex in vascular dementia rats. Kongsheng Zhenzhong pills may protect cognitive functions by affecting growth factors. | | |
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